Agilent, 799975-944, AdvanceBio RP-mAb Diphenyl, 4.6 x 50 mm, 3.5 µm

AdvanceBio RP-mAb Diphenyl, 4.6 x 50 mm, 3.5 µm. A reversed-phase diphenyl HPLC column with superficially porous particles and a wide (450 Å) pore size designed for mAbs and other larger proteins when alternate selectivity is needed or preferred.

Specifications:
Brand: AdvanceBio RP mAb Diphenyl
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: Diphenyl
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

**********The following product description is generated by AI and is for reference only. If you have any questions, please contact customer service.**********
The AdvanceBio RP-mAb Diphenyl, 4.6 x 50 mm, 3.5 µm column is designed for high-resolution reversed-phase chromatography of monoclonal antibodies and related biotherapeutics. Utilizing diphenyl bonded phase technology, this column provides complementary selectivity to C18 and C4 phases, enhancing the separation of protein variants and post-translational modifications. It is ideal for characterization of intact proteins and subunits, peptide mapping, and impurity profiling in pharmaceutical development and quality control environments.

This column is suitable for use with leading HPLC and UHPLC systems and delivers robust performance with excellent batch-to-batch reproducibility. It supports a wide range of mobile phase conditions, making it compatible with various workflows in biopharmaceutical research and process monitoring. AdvanceBio RP-mAb Diphenyl columns are engineered for high sample throughput and provide reliable resolution even for challenging samples. Laboratories involved in antibody drug development, biosimilar characterization, or process impurity analysis will benefit from its consistent performance and distinct selectivity.

For comprehensive biotherapeutic characterization, this column can be used alongside other AdvanceBio columns such as C18, C4, and peptide mapping columns to optimize separation strategies and meet evolving analytical demands.