Agilent, GKIB-025, AdvanceBio InstantAB HuIgG and RNase B N-glycan Library

AdvanceBio InstantAB HuIgG and RNase B N-glycan Library. Consists of 2 blended libraries of N-linked glycans whose reducing termini are derivatized with the fluorescent dye, InstantAB. The libraries were blended to provide a comprehensive profile of biantennary, high mannose and sialylated oligosaccharides.

Specifications:
Label: InstantAB
Unit: 70 pmol

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This comprehensive reference library is designed to support rapid identification and quantitation of N-glycans in biopharmaceutical research and quality control. It contains pre-labeled N-glycans derived from human immunoglobulin G and RNase B, processed using the InstantAB labeling system for streamlined sample preparation. The product enables precise glycan profiling through high-quality, consistent standards, ensuring reliable analytical results and reproducibility.

The library facilitates accurate retention time and structural assignment in workflows such as HILIC UHPLC with fluorescence and mass spectrometric detection, accelerating glycosylation analysis for monoclonal antibody development and glycoprotein characterization. It is ideal for laboratories engaged in biopharmaceutical development, biosimilarity assessments, and glycoengineering studies.

Optimized for use with Agilent AdvanceBio Glycan Mapping columns and fully compatible with systems such as Agilent 1260 Infinity II LC, 1290 Infinity II LC, and MassHunter Workstation software, the library enhances workflow efficiency and data confidence. It serves as a vital tool for developing robust methods for regulatory compliance and can be used alongside other Agilent AdvanceBio reference standards for comprehensive glycan analysis solutions.