Agilent, GKSP-106, AdvanceBio APTS Man8 / M8 N-glycan Standard

AdvanceBio APTS Man8 / M8 N-glycan Standard. N-glycan (oligomannose 8) labeled with 8-aminopyrene-1,3,6-trisulfonate (APTS), for use as a qualitative standard in applications such as capillary electrophoresis (CE).

Specifications:
Chemical Structure:
Label: APTS
Monoisotopic Mass: MWGlycan + 440.9647 = 2161.5565
Name: Man8
Oxford Name: M8
Standard Type: High Mannose-type Native N-Glycan
Unit: 60 pmol

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The AdvanceBio APTS Man8 M8 N-glycan Standard is a high-purity, well-characterized glycoconjugate designed for use in glycan analysis workflows. Labeled with aminopyrene trisulfonate (APTS), this standard enables rapid and accurate profiling of high mannose N-glycans, specifically the Man8 variant, which is critical for biopharmaceutical characterization and quality control. It is ideally suited for laboratories conducting monoclonal antibody development, glycoprotein research, or supporting biosimilar comparability studies. Compatible with platforms utilizing capillary electrophoresis with laser-induced fluorescence detection, including Agilent Fragment Analyzer and similar systems, this standard provides robust reference retention times and quantitation benchmarks. It supports consistent data normalization and method validation across experiments, improving confidence in glycan structure assignment. This standard is also a valuable tool for verifying system performance and optimizing separation conditions in high-throughput environments. When used alongside other AdvanceBio glycan standards and sample preparation kits, it enhances workflow efficiency and reproducibility. Suitable for regulatory environments, it facilitates compliance with glycosylation analysis requirements for therapeutic protein development.