Agilent, GKSP-107, AdvanceBio APTS Man9 / M9 N-glycan Standard

AdvanceBio APTS Man9 / M9 N-glycan Standard. N-glycan (oligomannose 9) labeled with 8-aminopyrene-1,3,6-trisulfonate (APTS), for use as a qualitative standard in applications such as capillary electrophoresis (CE).

Specifications:
Chemical Structure:
Label: APTS
Monoisotopic Mass: MWGlycan + 440.9647 = 2323.6093
Name: Man9
Oxford Name: M9
Standard Type: High Mannose-type Native N-Glycan
Unit: 60 pmol

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This analytical standard provides a highly purified N-glycan species corresponding to the Man9GlcNAc2 structure, commonly referred to as M9. It is specifically labeled with 2-aminopyridine (APTS), enabling sensitive detection through fluorescence and compatibility with advanced analytical techniques such as UHPLC, LC-FLD, and CE-LIF. Designed for use in the characterization and quantification of N-glycans in biopharmaceutical development and quality control, this standard supports the rigorous requirements of glycoprotein analysis workflows. It is ideal for validating glycan profiling methods, optimizing separation parameters, and confirming system performance in complex sample matrices. Common applications include the assessment of monoclonal antibody glycosylation patterns and ensuring regulatory compliance during therapeutic protein production. This product is fully compatible with Agilent AdvanceBio Glycan Mapping columns and associated fluorescence detection modules. It also serves as a reliable reference sample for mass spectrometry-based glycan analysis and offers seamless integration into established glycan release and labeling protocols. Reliable and consistent, this standard enables high-precision comparative studies and supports method development for biotherapeutic research, R and D, and manufacturing environments. For optimal results, pair with complementary Agilent sample preparation kits and detection systems to achieve confident identification and quantification outcomes.