Agilent, PL1180-1301, AdvanceBio SEC 300Å, 7.8 x 50 mm, 2.7 µm, LC guard column

AdvanceBio SEC 300Å, 7.8 x 50 mm, 2.7 µm, LC guard column. To protect and extend the lifetime of a longer analytical SEC column.

Specifications:
Brand: AdvanceBio SEC
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 7.8 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 5000 Da
Molecular Weight Upper Limit: 1250000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 2.7 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 300 Å
Pressure Rating: 400 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: 0.02% Sodium Azide
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

**********The following product description is generated by AI and is for reference only. If you have any questions, please contact customer service.**********
This high-performance guard column is engineered for robust protection and extended lifetime of size exclusion chromatography (SEC) analytical columns in biopharmaceutical workflows. Featuring a 300 Angstrom pore size, 2.7 micron particle size, and compact 7.8 x 50 millimeter format, it efficiently removes particulates and strongly adsorbed sample components, preserving analytical column integrity and optimizing reproducibility.

Optimized for protein and biomolecule characterization, the guard column supports the precise analysis of monoclonal antibodies, aggregates, fragments, and other biologics across a wide range of molecular weights. It is ideally suited for workflows in therapeutic protein development, quality control, formulation screening, and process monitoring. The column is fully compatible with popular HPLC and UHPLC platforms, and seamlessly integrates with Agilent’s AdvanceBio SEC columns as well as other short-bed SEC analytical columns.

The rugged design ensures consistent performance under standard SEC operating conditions, accommodating common mobile phases and flow rates for reliable, low-dispersion results. Use of this guard column enhances column longevity and data quality in demanding analytical applications. For optimal results, pair this guard column with Agilent AdvanceBio SEC analytical or preparative columns, and operate within manufacturer-recommended parameters for robust, reproducible separations.