Agilent, PL1180-3301, AdvanceBio SEC 300Å, 7.8 x 150 mm, 2.7 µm, LC column

AdvanceBio SEC 300Å, 7.8 x 150 mm, 2.7 µm, LC column. A size exclusion column for efficient aggregate analysis of proteins, including monoclonal antibodies. The resolving range is 5-1,250 kDa.

Specifications:
Brand: AdvanceBio SEC
Hardware: SS
Inner Diameter (ID): 7.8 mm
LC Platform: Stainless Steel
Length: 150 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 5000 Da
Molecular Weight Upper Limit: 1250000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 2.7 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 300 Å
Pressure Rating: 400 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: 0.02% Sodium Azide
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

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The AdvanceBio SEC 300Å, 7.8 x 150 mm, 2.7 µm LC column is designed for high-resolution size exclusion chromatography of biomolecules, including monoclonal antibodies, proteins, and aggregates. Engineered with a 300 angstrom pore size and a sub-3-micron particle diameter, this column enables fast, accurate analysis of molecular size distributions, aggregate content, and fragment profiles in biotherapeutic research and quality control.

Its compact format delivers rapid throughput without compromising resolution, making it suitable for both method development and routine analysis in pharmaceutical, biotechnology, and research laboratories. The chemically stable, rigid particle design ensures long column lifetimes and consistent performance, even under demanding analytical conditions.

This column is compatible with major liquid chromatography systems, including Agilent InfinityLab and 1100, 1200, and 1260 series LC instruments. It integrates seamlessly with UV, fluorescence, or mass spectrometry detectors, supporting both qualitative and quantitative workflows. For comprehensive biomolecule characterization, it operates optimally with aqueous mobile phases commonly used in protein and monoclonal antibody analysis. Pairing this column with other AdvanceBio products—such as SEC calibration standards or guard columns—provides a robust platform for reliable and reproducible biopharmaceutical analysis across research and regulated environments.