Agilent, PL1580-1301, AdvanceBio SEC 300Å, 4.6 x 50 mm, 2.7 µm, LC guard column

AdvanceBio SEC 300Å, 4.6 x 50 mm, 2.7 µm, LC guard column. To protect and extend the lifetime of a longer analytical SEC column.

Specifications:
Brand: AdvanceBio SEC
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 5000 Da
Molecular Weight Upper Limit: 1250000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 2.7 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 300 Å
Pressure Rating: 400 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: 0.02% Sodium Azide
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

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Designed for robust protein and biopharmaceutical analysis, this AdvanceBio SEC 300 Angstrom guard column enables high-resolution size exclusion chromatography. With 2.7 micron particle size and dimensions of 4.6 x 50 millimeters, it is optimized for precise separation of proteins, antibodies, and aggregates, supporting critical quality assessments and stability studies in pharmaceutical and academic research.

Functioning as a protective guard, this column extends the lifespan of analytical and preparative SEC columns by trapping particulates and contaminants, ensuring consistent performance and reducing instrument downtime. Its engineered pore size of 300 Angstroms is ideal for characterization of monoclonal antibodies, biosimilars, and other large biomolecules, providing accurate molecular weight distribution profiles and aggregate quantification.

Compatible with a wide array of liquid chromatography systems, including Agilent HPLC and UHPLC instruments, the column seamlessly integrates with full-size AdvanceBio SEC columns for comprehensive workflow solutions. It is suitable for use in laboratories focused on drug development, formulation, and quality control. Pairing with AdvanceBio SEC analytical columns further enhances robustness and efficiency, offering reliable data for regulatory filings or routine analyses. The column features low non-specific binding for high sample recovery, resulting in reproducible, high-quality chromatographic results across diverse protein samples.