Agilent, PL1912-1301, PLRP-S 300Å, 2.1 x 50 mm, 3 µm

PLRP-S 300Å, 2.1 x 50 mm, 3 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 3 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 300 Å
Pressure Rating: 275 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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This high-performance reversed-phase chromatography column is engineered for advanced biomolecule separations. Featuring a 300 angstrom pore size and a robust polystyrene-divinylbenzene matrix, it excels in the analysis of proteins, large peptides, and other macromolecules that require enhanced pore accessibility. The 2.1 mm internal diameter and 50 mm column length, combined with 3 micron particle size, ensure high resolution, sharp peak shapes, and reproducible results for both analytical and microbore LC workflows.

Ideal for use in proteomics, biopharmaceutical development, and quality control laboratories, this column efficiently separates challenging analytes, including monoclonal antibodies, protein fragments, and post-translationally modified species. Its polymeric base provides superior chemical and pH stability compared to traditional silica-based products, supporting both routine and method development applications.

Compatible with a wide range of HPLC and UHPLC systems from Agilent and other major manufacturers, this column integrates seamlessly into existing workflows. It pairs effectively with Agilent PLRP-S guard columns and advanced detection platforms, supporting both mass spectrometry and UV detection. Designed for durability and consistent performance, it is an excellent choice for demanding applications in life science and pharmaceutical research.