Agilent, PL1912-1502, PLRP-S 1000Å, 2.1 x 50 mm, 5 µm

PLRP-S 1000Å, 2.1 x 50 mm, 5 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 5 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 1000 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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This polymeric reversed-phase HPLC column features 1000 angstrom pore size, a 2.1 x 50 mm format, and 5 micron particle size, optimized for the high-resolution analysis of large biomolecules, including peptides, proteins, and oligonucleotides. Engineered with rigid, highly cross-linked polystyrene-divinylbenzene (PS-DVB) media, it provides excellent stability across a wide pH range and superior chemical durability, facilitating the use of aggressive cleaning protocols and ensuring consistent performance in demanding workflows.

Its broad pore size makes it particularly well-suited for size-exclusion and reversed-phase separations of high molecular weight analytes in analytical and preparative research settings. Common applications include characterizing biopharmaceuticals, protein variants, enzyme digests, and synthetic oligonucleotides. This column is compatible with Agilent and other major HPLC instruments, fitting seamlessly into established LC-MS workflows and complementing a wide range of mobile phase conditions.

Designed to deliver reproducible separations and improved analyte recovery, this solution supports method development and routine analysis in regulated and research laboratories. For extended capabilities, combine with other PLRP-S columns of varying pore or particle sizes to optimize separations or pair with Agilent HPLC systems and detectors for integrated system solutions.