Cytiva, 29722782, Biacore™ 8 series SPR systems

Biacore 8K SPR system Unlock the full potential of your research with Cytiva's Biacore™ 8 series surface plasmon resonance (SPR) platform. Designed for high-throughput and high-sensitivity applications, this system features 16 flow-cells, delivering unparalleled efficiency and high-quality data for affinity, kinetics, and concentration analysis. All systems are built for analysis in a GxP-regulated environment. • Rapid hit selection: Screen 2,300 samples in just 24 hours, quickly identifying the most relevant hits. • High sensitivity and robustness: Perform high-quality binding analysis, even for complex molecules like GPCRs in crude membrane preparations or bivalent analytes. • Operational efficiency: Manage up to twelve 96- or 384-well microplates with temperature control for samples, reagents, and assay runs. • Streamlined assay development: Utilize eight needles and 16 flow-cells for rapid multirun evaluations and method queueing, enabling parallel assay development. • Easy method and data transfer: Seamlessly transfer methods and data to other labs, Biacore™ 8 series or Biacore™ 1 series SPR systems. • Cost-efficient solution: Integrated autosampler and data management offers versatility for a wide range of applications and molecules, ultimately reducing costs. Cytiva’s Biacore™ 8 series SPR systems, featuring 16 flow-cells, are engineered to tackle the toughest challenges in small molecule and biotherapeutic screening and characterization. This SPR platform delivers high-quality affinity, kinetics, concentration, and yes/no binding data with exceptional capacity and sensitivity. Integrated plate handling for up to 12 plates eliminates the need for external automation, ensuring seamless and precise results for cutting-edge research. System Configurations Biacore™ 8K and Biacore™ 8K+ systems differ in microplate hotel capacity but share the following features:

	Biacore™ 8K system	Biacore™ 8K+ system
Sensitivity	10-6 to 0.5 s-1	10-6 to 0.5 s-1
Short term noise	Typically < 0.02 RU (RMS)	Typically < 0.02 RU (RMS)
Analysis temperature	4°C to 40°C	4°C to 40°C
Data collection rate	1 or 10 Hz	1 or 10 Hz
Sample capacity	up to 4 × 384-well microplates	up to 12 × 384-well microplates
Flow cell addressing	Single or pairwise	Single or pairwise
Unattended run time	60 h unattended run time	72 h unattended run time

Biacore™ Insight Software Biacore™ Insight software offers unified instrument control and data evaluation, allowing straightforward transfer of methods to Biacore™ 1 series and Biacore™ 8 series SPR systems. Enhance functionality with optional application-specific software extensions and machine learning-based evaluation tools, reducing your time to results. View the Biacore™ Insight software product page . Biacore™ Consumables Cytiva provides a range of tools to ensure reliable and reproducible data with minimal effort: Series S sensor chips : All sensor chips are produced in an quality-controlled environment. Compatible with Biacore™ SPR systems, these sensor chips support analysis of interactions from small organic molecules to viruses.

Kits, buffers, and reagents : Reduce assay development time with consistent capture of antibodies and molecules via common tags. Ready-made buffers and solutions ensure reliable results and ease of use.
Predefined Methods Biacore™ Insight control software includes predefined methods with application-relevant settings for major assays. Start experiments in minutes using these methods and Biacore™ SPR consumables. What’s included Included in Biacore™ 8 series systems are the instrument, table with wheels, waste container, 2 licenses for Biacore™ Insight Software (product code 29310602), and 2 licenses for Biacore™ Insight Extended Screening Extension (product code 29310610).