Merck, 1.52022.0001, Chromolith® HighResolution RP-18 endcapped

Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure. Chromolith® HighResolution RP-18 endcapped columns have macropores with 1.15 μm diameter, giving a column efficiency exceeding 140,000 plates/meter. The mesopores are 15 nm (150 Å), the surface modification is octadecylsilane with full end-capping. Chromolith® HighResolution RP-18 endcapped columns fall under the USP L1 Classification. The column efficiency is comparable to a 2.7 to 3 μm particle size fully porous particulate column. Chromolith® HighResolution RP-18 endcapped columns are perfectly suitable for LC-MS applications. The column dimension of 100 mm length and 4.6 mm I.D. is the best choice for high resolution separations of complex compound mixtures on any HPLC System. The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables: —Rapid separations at very low column back-pressure —High matrix tolerance, allowing time and cost savings with simplified workflows —Cost-savings due to extended column lifetimes —Connection of columns, flow gradients and the use of mobile phases with higher viscosity