Thermo Fisher, 16102, Dynabeads™ Epithelial Enrich

Thermo Fisher, 16102, Dynabeads™ Epithelial Enrich Dynabeads Epithelial Enrich consist of 4.
5-μm superparamagnetic beads coupled to a monoclonal mouse anti-human EpCAM antibody and are intended for isolation of circulating epithelial tumor cells (CTCs) from liquid biopsy samples. The sensitive isolation method provided by Dynabeads Epithelial Enrich is necessary given the low number of CTCs in liquid biopsy samples. The isolated CTCs remain attached to the beads throughout the process.
For downstream molecular or proteomic analysis, the cells can be directly lysed while still attached to the beads. RT-PCR can be performed for amplification and quantification of target nucleic acids. CTC isolation and any subsequent bead-based proteomic or molecular applications can be performed manually or automated using the KingFisher Apex purification system.
Benefits of Dynabeads Epithelial Enrich include:High sensitivity and specificity isolation of CTCs from liquid biopsy samplesFast and efficient isolation of viable CTCsAutomation user guide and script available for high-throughput enrichment using the KingFisher Apex instrumentCell Type: Tumor Cells, Epithelial Cells
Includes: 5 mL Dynabeads coated with the monoclonal antibody BerEP4 against the human epithelial antigen, EpCAM
Isolation Technology: Depletion, positive isolation for molecular applications
No. of Cells: Processes ∼4 x 109cells total
Output Viability: >95%
Product Line: DYNAL™, Dynabeads™
Purity or Quality Grade: Research Grade
Quantity: 5 mL
Reactivity: Human
Sample Type: PBMC, Blood
Shipping Condition: Room Temperature
Starting Material Cell No.: 2 x 107PBMCs per isolation
Target Species: Human
Product Type: Antibody Coated Bead
Unit Size: Each