Thermo Fisher, 21666, DMP (dimethyl pimelimidate)

50 mg Thermo Scientific Pierce DMP is dimethyl pimelimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of a 7-atom spacer arm.
Features of dimethyl pimelimidate:
•Reactive groups:imidoester(both ends)
•Reactive towards:amino groups (primary amines)
• Mid-length reagent of three similar imidoester crosslinkers, which include DMA, DMP and DMS
• Water-soluble
• Imidoesters react with amines at alkaline pH values (pH 8-10) to form amidine bond
• Amidine bond retains net charge character of protein primary amine to which it reacts
• Reversible at high pH values
• Tool for study of quarternary structure of proteinsProduct ReferencesCrosslinker Application Guide -- search for recent literature references for this productCell Permeability: Yes
Description: DMP
Form: Powder
Labeling Method: Chemical Labeling
Molecular Weight (g/mol): 259.
17
PEGylated: No
Product Line: Pierce™
Quantity: 50 mg
Reactive Moiety: Imidoester
Shipping Condition: Ambient
Solubility: Water
Spacer Arm Length: 9.
2 Å
Water Soluble: Yes
Chemical Reactivity: Amine-Amine
Cleavable: No
Crosslinker Type: Homobifunctional
Format: Standard
Product Type: Crosslinker
Spacer: Short (<10 Å)
Unit Size: Each