Thermo Fisher, 27-1601-09, 2'-Fluoro-Bz-A Phosphoramidite, standard grade, 20-400 finish bottle

Thermo Fisher, 27-1601-09, 2'-Fluoro-Bz-A Phosphoramidite, standard grade, 20-400 finish bottle 2'-Fluoro-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.
31P NMR Purity: ≥98%
Chemical Name or Material: 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-fluoroadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Description: Base: ABase Protection: Bz
For Use With (Application): Oligonucleotide synthesis
For Use With (Equipment): Expedite Synthesizers
Form: Powder
Format: Amber bottle (20-400 finish neck style)
Grade: Standard
Molecular Formula: C47H51FN7O7P
Molecular Weight (g/mol): 875.
92 g/mol
Nucleic Acid Type: RNA
Nucleoside Type: Adenosine (A)
Product Type: 2in-Fluoro-Bz-A CEP
Purity: >98% (HPLC)
Quantity: 0.
25 g
Reagent Features: 2in-Fluoro modified
Reagent Type: Phosphoramidite
Shipping Condition: Room Temperature
Unit Size: Each