Thermo Fisher, A31804, Vitronectin (VTN-N) Recombinant Human Protein, Truncated

Thermo Fisher, A31804, Vitronectin (VTN-N) Recombinant Human Protein, Truncated Vitronectin (VTN-N) is a recombinant human protein that provides a defined surface for feeder-free culture of human pluripotent stem cells (PSCs). When used with Essential 8™ Medium (A1517001), vitronectin (VTN-N) has been proven to maintain pluripotency and normal growth characteristics in multiple PSC lines. In addition, vitronectin (VTN-N) has been shown to support PSC growth for >50 passages without any signs of karyotypic abnormalities and to maintain the ability of PSCs to differentiate into all three germ line lineages. As published by Guokai Chen et al. (1) in the laboratory of James Thomson, the VTN-N variant of vitronectin supports human pluripotent stem cell attachment and survival better than wild-type vitronectin when used in conjunction with Essential 8™ Medium.
Vitronectin (VTN-N) is:
•Optimized—designed in the laboratory of James Thomson for use with Essential 8™ Medium
•Defined—for reduced variability in your PSC cultures
•Cost effective—for economical and scalable PSC cultureOptimized and Defined SurfaceUnlike standard basement membrane extracts (BMEs), vitronectin (VTN-N) was designed in the laboratory of James Thomson for use with Essential 8™ Medium and has been shown to support human pluripotent stem cell attachment and survival better than wild type vitronectin. Vitronectin (VTN-N) provides an optimal environment for feeder-free pluripotent stem cell culture.
Reduce VariabilityVitronectin (VTN-N) is a defined, recombinant human protein that reduces variability in your PSC cultures compared to human-plasma derived vitronectin and standard basement membrane extracts (BMEs).
Cost EffectiveWhen used with Essential 8™ Medium, vitronectin (VTN-N) provides a cost effective, defined system for feeder free culture of human pluripotent stem cells (PSCs).
Commercialized in Partnership with Cellular Dynamics International.
Concentration: 500 μg⁄ml
Expression System: E. coli
Protein Form: Recombinant
Protein Subtype: Vitronectin
Purity or Quality Grade: Cell Culture Grade, Endotoxin-Screened
Quantity: 10 mL = 5 mg
Research Category: Stem Cell Research
Shipping Condition: Dry Ice
Volume (Metric): 10 mL
For Use With (Application): Stem Cell Culture
Form: Liquid
Recombinant: Recombinant
Species: Human
Unit Size: Each