Thermo Fisher, J61391.AK, Citrate, 0.5M buffer soln., pH 3.0

Citrate, 0.
5M buffer soln., pH 3.
0 Citrate is an intermediate in the TCA cycle and fatty acid synthesis. It is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA. It has anticoagulant activity and is a calcium chelator. Its function is to break protein cross-links; thus, unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
CAS: 6132-04-3
IUPAC Name: trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate
Molecular Formula: C6H9Na3O9
InChI Key: NLJMYIDDQXHKNR-UHFFFAOYSA-K
SMILES: O.
O.[Na+].[Na+].[Na+].
OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
Comment: Buffer is made by dissolving ingredients in 18.
2 megahom, UV treated water, filtered through submicron filter
Form: Clear Liquid
pH: 3.
0 ± 0.
15