Product Description
Tacrolimus, 99+% Interacts with the immunophilins cyclophilin and FKBP-12.
Tacrolimus is used as an immunosuppressive drug that blocks T cell proliferation in vitro. Further, it is used as a research tool in chemically induced dimerization applications.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
CAS: 104987-11-3
IUPAC Name: (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo[22.
3.
1.
0⁴,⁹]octacos-18-ene-2,3,10,16-tetrone hydrate
Molecular Formula: C44H71NO13
InChI Key: NWJQLQGQZSIBAF-HZXKVGIDSA-N
SMILES: O.
CO[C@@H]1CC(CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
Assay from Supplier's CofA: ≥99.
0% (HPLC)
Form: Powder
Appearance (Color): White
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