Waters, 186001840, Symmetry Shield RP18 Prep Column, 100Å, 7 µm, 19 mm X 300 mm, 1/pk

These reversed-phase columns contain Waters patented embedded polar group technology that “shields” the silica’ residual silanol surface from highly basic analytes. The reduced silanol activity for the SymmetryShield RP18 column significantly improves peak shape and resolution.

Specifications
Chemistry: C18
Separation Mode: Reversed Phase
Particle Substrate: Silica
pH Range Min: 2 pH
pH Range Max: 8 pH
Temperature Limits: 45 C
Maximum Pressure: 6000 psi (415 Bar)
Endcapped: Yes
Bonding Technology: Shield RP18
Silanol Activity: Low
Particle Shape: Spherical
Particle Size: 7 µm
Endfitting Type: Waters
Pore Size: 100 Å
Format: Prep Column
Surface Area: 335
System: HPLC Preparative
Technique: LC/MS, LC
USP Classification: L1
Inner Diameter: 19 mm
Length: 300 mm
Carbon Load: 17 %
UNSPSC: 41115709
Brand: Symmetry
Product Type: Preparative Columns
Units per Package: 1 pk

Additional Information
Symmetry Shield RP18 Prep Column, 100Å, 7 µm, 19 mm X 300 mm, 1/pk Deliver consistent, repeatable chromatographic findings throughout the lifespan of a novel medicine product by using the Symmetry Shield RP18 column. The lab equipment delivers great consistency, making it perfect for applications like developing new analytical techniques for cutting-edge pharmaceutical and biopharmaceutical goods. The analytical column's goal is to reduce the range of possible column specifications so that you can get consistent findings. This is accomplished by making sure that the surface coverage parameters are the strictest in the sector. As a result, there are fewer resolution shifts and more consistent batch-to-batch and column-to-column outcomes. The proprietary embedded polar group technology from Waters is present in the Symmetry Shield RP18 column. The purpose of this method is to "shield" the column's remaining silanol surface from very basic analytes. The Symmetry Shield RP18 column's peak shape and resolution are greatly improved as a result of the decreased silanol activity that results. Superior peak form is achieved across a significant pH range due to the high bonding density and low residual silanol activity of the packing materials of the Symmetry Shield RP18 column. As a result, you may quickly improve your approach and operate at neutral or low pH levels without having to worry about losing the peak shape. The Symmetry Shield RP18 column possesses silanol activity compared to the conventional C18 and C8 columns, which results in decreased retention for basic chemicals. The Symmetry Shield RP18 column is thus perfectly suited to serve as a top-notch instrument for method development. Use the LCGC Certified Clear Glass 12 x 32 mm Screw Neck Vial, with Cap and Preslit PTFE/Silicone Septum, 2 mL Volume, 100/pk to store your analytes and samples in safe storage. Based on LC/GC standards, the vials adhere to the strictest requirements for dimensional tolerances, UV cleanliness, and MS cleanliness. These vials are made to meet the requirements of LC/GC certification and to take into account all aspects of use, including volatility, tray design, and needle design. An HPLC test is performed on every vial to check for traces of compounds introduced during processing and manufacture.

FAQ
What Does the “RP” in “RP18” Mean? “RP” refers to reverse-phase chromatography. What Is The Maximum Pressure That The Symmetry Shield RP18 Prep Column Can Sustain? This particular Symmetry Shield RP18 Prep Column is able to tolerate a maximum of 6000 psi (415 Bar) pressure.