Merck, I2136-1ML, Anti-Human IgG (Fc specific) antibody produced in goat

The product binds human IgG and does not bind other human Igs. Immunoglobulins comprise of two fragment antigen binding (Fab) and one fragment crystallizable (Fc) domains. The gene encoding IgG gene cluster is located on human chromosome 14. Anti-Human IgG (Fc specific) antiserum is produced in goat using purified human IgG, Fc fragment, as the immunogen. Affinity isolated antibody is obtained from goat anti-human IgG antiserum by immunospecific purification which removes essentially all goat serum proteins, including immunoglobulins, which do not specifically bind to the Fc fragment of human IgG.