Cytiva, 17531604, Capto™ Q ion exchange chromatography resin

Capto Q, 5 L Designed to meet the demands of modern, large-scale manufacturers Capto Q’s shorter processing times can reduce exposure of the target protein. • Strong anion exchanger for high-productivity capture and intermediate purification when high volume throughput is essential. • High dynamic binding capacity at high flow raises productivity. • High-volume throughput cuts process times. • Cost-effective processing with smaller unit operations. • Resin fulfills industrial demands for security of supply, robust performance, and regulatory support. Offers increased productivity Capto Q is designed for capture and intermediate purification of proteins from large feed volumes. It is composed of a rigid, high-flow agarose matrix modified with dextran surface extenders and a strong quaternary ammonium (Q) anion exchanger. The combination of high volume throughput and high dynamic binding capacity for Capto Q raises the productivity in industrial downstream processes. Durable and stable Capto Q withstands effective and rigorous cleaning-in-place (CIP) procedure and the chemical stability supports long resin lifetime. Prepacked columns and other formats Capto Q is available in the following formats: Process development scale – prepacked PreDictor Capto Q filter plates – 96-well plates for high-throughput screening or process development. PreDictor Capto Q RoboColumn™ units – miniaturized columns for high-throughput process development. HiScreen Capto Q columns – optimized for method and process development. Validation columns , scale-down columns for robust and reproducible process validation and process development (Tricorn™ format). f(x) column , prepacked and precharacterized chromatography column for fast and accurate mechanistic modeling. Lab/research scale – prepacked for manual purification HiTrap Capto Q columns – for easy use with a syringe, peristaltic pump, or chromatography system. Lab/research scale – prepacked for automated purification and analysis HiTrap Capto Q columns – for easy use with a syringe, peristaltic pump, or chromatography system. Process-scale purification – prepacked ReadyToProcess Capto Q columns – 1 L and larger columns for clinical manufacturing that avoid the need for cleaning and cleaning validation.