Thermo Fisher, O6185, Oregon Green™ 488-X, Succinimidyl Ester, 6-isomer

Oregon Green™ 488-X, Succinimidyl Ester, 6-isomer The amine-reactiveOregon Green™ 488-X, succinimidyl estercan be used to can be used to create green fluorescent bioconjugates with excitation/emission maxima ∼496/524 nm. This fluorinated analog of fluorescein overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa(pKa∼ 4.
7 versus 6.
4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range. This reactive dye contains an additional seven-atom aminohexanoyl spacer ('X') between the fluorophore and the succinimidyl ester group. This spacer helps to separate the fluorophore from its point of attachment, potentially reducing the interaction of the fluorophore with the biomolecule to which it is conjugated.
Chemical Reactivity: Amine
Emission: 524
Excitation: 496
Label or Dye: Oregon Green™ 488
Product Type: Succinimidyl Ester
Quantity: 5 mg
Reactive Moiety: Active Ester, Succinimidyl Ester
Shipping Condition: Room Temperature
Label Type: Classic Dyes
Product Line: Oregon Green™
Unit Size: Each