Waters, 176004596, BioResolve SEC mAb Column with BioResolve SEC mAb Guard, 200Å, 2.5 µm, 4.6 x 150 mm, 1/pk with mAb Size Variant Standard

The BioResolve SEC mAb 4.6 x 150 mm Column and Guard contains 2.5 µm BEH particle technology and is application specifically tested with the mAb Size Variant Standard to ensure accurate and highly reproducible quantitation of monoclonal antibody (mAb) monomers from frequently associated high molecular weight aggregates (≥300,000 Da) and lower molecular weight fragments (e.g., ≤100,000 Da).  This column is also shipped with Water mAb Size Variant Standard at no extra charge (p/n: 176004593).

Specifications
Chemistry: SEC
Separation Mode: SEC
Particle Substrate: Hybrid
pH Range Min: 2.5 pH
pH Range Max: 8 pH
Temperature Limits: 60 C
Maximum Pressure: 4500 psi (310 Bar)
Endcapped: No
Bonding Technology: Diol (OH)
Silanol Activity: Low
Molecular Weight Range Min: 10000
Molecular Weight Range Max: 450000
Particle Shape: Spherical
Particle Size: 2.5 µm
Endfitting Type: Parker-style
Pore Size: 200 Å
QC Tested: Protein
Format: Online Column
Packing Solvent: 10% acetonitrile/90% 25 mM sodium phosphate pH 7.0 + 100 mM KCl
Surface Area: 220
System: HPLC
Particle Technology: BEH
Technique: LC
USP Classification: L33
Inner Diameter: 4.6 mm
Length: 150 mm
Carbon Load: 12 %
eCord: Yes
UNSPSC: 41115711
Application: Protein
Brand: BioResolve
Product Type: Columns
Units per Package: 1 pk

Additional Information
BioResolve SEC mAb Column with BioResolve SEC mAb Guard, 200Å, 2.5 µm, 4.6 x 150 mm, 1/pk with mAb Size Variant Standard For monoclonal antibody quantitation, you want an mAb column that can handle analytical challenges every step of the way. That’s why we’re happy to provide the BioResolve SEC mAb Column, designed to do exactly that and so much more. At the heart of the BioResolve SEC mAb Column is Ethylene-Bridged Hybrid (BEH) particle technology that greatly enhances separation performance while upholding chemical stability. You need only look at the wide and usable pH range that this column offers to see that it can handle your mAb separations and analyses with ease. Tell your lab manager now that you want the BioResolve SEC mAb Column at your command. This BioResolve SEC mAb Column also comes with the BioResolve SEC mAb Guard. What is this guard column? Designed to remove contaminants from the mobile phase stream, the BioResolve SEC mAb Guard column ensures miniscule particulate contaminants don’t enter your analytical column and foul it. Plus, when this guard becomes worn by filtering out too many contaminants, you can simply replace it with another genuine replacement from Waters. Please note that this guard column is no replacement for proper sample purification protocols. The BioResolve SEC mAb Column is specifically designed to return the accurate, reproducible quantitation of monoclonal antibody monomers from both higher and lower molecular weight fragments. But to ensure you get exactly this kind of performance right out of the box, each and every BioResolve SEC mAb Column must undergo strict QC processes before being shipped to you. Speaking of QC, make sure to stock up on the mAb Size Variant Standard designed to help benchmark LC systems for proper performance. At Waters, we’re happy to help you transform your mAb analyses for the better. But before you check out, make sure to check out all of the other incredible products, resources and services we have to offer. Shop lab equipment to explore our offerings.

FAQ
What’s the BioResolve SEC mAb Column’s Silanol Activity? The BioResolve SEC mAb Column offers low silanol activity.