Abcam, ab273575, Anti-Galectin 13/PLAC8 + Galectin-16 antibody [EPR23383-89] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal Galectin 13/PLAC8 antibody. Carrier free. Suitable for IP, IHC-P, WB and reacts with Human, Recombinant fragment - Human samples.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR23383-89,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Human,
Applications:WB, IP, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab273575 is the carrier-free version of
ab272716
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Galectin 13 also known as PLAC8 or Galectin-16 is a type of protein that belongs to the Galectin family. It functions by binding to β-galactoside sugars which allows it to interact with glycoproteins and cell surfaces. The protein has a mass of approximately 16 kDa. Expression occurs mainly in the placenta suggesting a role in reproductive physiology but it has also been identified in other tissues to lesser extents including the colon.
Biological function summary
Galectin 13/PLAC8 Galectin-16 plays significant roles in modulating immune responses and cell-cell interactions. It appears integral to the maintenance of an immune-tolerant environment particularly in the placenta supporting successful implantation and pregnancy. The protein might operate as part of a complex involving other members of the Galectin family to regulate immune checkpoints and enhance cell adhesion processes.
Pathways
Galectin 13/PLAC8 Galectin-16 contributes to essential biological pathways linked to cell signaling and immune system modulation. It influences the JAK/STAT signaling pathway which is vital for cell proliferation and differentiation modes. This involvement supports balanced communication within immune responses and the protein interacts with other Galectins and perhaps other signaling molecules within this context.
Alterations in Galectin 13/PLAC8 Galectin-16 levels have associations with preeclampsia a complex pregnancy disorder marked by hypertension and organ dysfunction. Studies illustrating its role show connections to inflammatory conditions that might affect pregnancy outcomes. Its interactions with other proteins such as Galectin-1 highlight potential mechanisms in placental pathophysiology and broader implications in immune-mediated disorders.