Agilent, 103595-100, Seahorse XF Mito Tox Assay Kit

Seahorse XF Mito Tox Assay Kit. Each kit contains six (6) single-use pouches. Each pouch contains one (1) each of oligomycin, FCCP, and rotenone/antimycin A. For use with Seahorse XF Pro analyzer only

Specifications:
Assay Wells: 6 x 96-well assays
Assays per Kit: 6
For Use With: Seahorse XF Pro Analyzer
Kit Contents: 6 full plate assays
Shipping Condition: Ambient Temperature
Storage Temp Conditions: Store at room temperature

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The Agilent Seahorse XF Mito Tox Assay Kit is a specialized reagent kit designed for the rapid and reliable detection of mitochondrial toxicity in live cells. Ideal for drug discovery, toxicology, and mitochondrial research, the assay enables real-time measurement of mitochondrial function, particularly evaluating how test compounds affect cellular respiration and ATP production. Utilizing a simple workflow, researchers can conveniently assess multiple samples in parallel, gaining kinetic data on mitochondrial impairment. This kit is optimized for use with Agilent Seahorse XF analyzers, including the XFe and XFp systems, providing seamless integration for high-throughput screening and predictive toxicology studies. Applications range from early-stage compound screening to detailed mechanistic studies involving mitochondrial dysfunction in diseases such as neurodegeneration, cardiovascular disorders, or metabolic syndromes. The assay is compatible with a range of cell types, including primary cells and established cell lines, and can be used alongside other Seahorse XF assays for comprehensive metabolic profiling. Each kit contains pre-formulated reagents, positive control compounds, and a detailed protocol to ensure reproducible and efficient results. The Seahorse XF Mito Tox Assay Kit empowers researchers to identify mitochondrial liabilities early, facilitating informed decision-making in biomedical research and pharmaceutical development.