Merck, MMHE-44K-15, MILLIPLEX® Mouse Metabolic Hormone Expanded Panel - Metabolism Multiplex Assay

Metabolic syndrome is a cluster of conditions that occur together; it includes increased blood pressure, elevated insulin levels, excess body fat around the waist and abnormal cholesterol levels.Key features of metabolic syndrome include insulin resistance, glucose intolerance, hypertension, dyslipidemia and central obsesity- all of which are risk factors for atherosclerosis, coronary heart disease, type 2 diabetes, kidney disease, and even premature death.Adults with metabolic syndrome show a low-grade inflammation, whose link with obesity may be dysregulated adipocyte production of pro- and anti-inflammatory factors. Consequently, research done in this area covers multi-faceted fields of cytokines, acute phase proteins, diabetes, and obesity related hormones, as well as other cardiovascular disease biomarkers.The MILLIPLEX® Mouse Metabolic Hormone Expansion Panel is a 15-plex kit to be used for the simultaneous quantification of any or all of the following analytes in tissue/lysate and culture supernatant samples and mouse serum or plasma: Amylin Active, C-Peptide 2, Ghrelin, GIP, GLP-1 Active or GLP-1 Total, Glucagon, IL-6, Insulin, Leptin, MCP-1, PP, PYY, Resistin, Secretin, and TNFα.Note: GLP-1 Active an GLP-1 Total cannot be run together in the same assay.