Sartorius, 110.5118-2, CIMac PrimaS® 0.1 mL Analytical Column (2 µm)

CIMac PrimaS® is a key player within BIA’s family of high-performance chromatography products for analysis and purification of mRNA.

CIMac Analytical Columns are short-bed high-performance monolithic columns offering all the advantages of CIM® monolithic technology. Their small volume and short column length allow the operation at high volumetric flow rates enabling them to receive the information about the product quantity and purity in just a few minutes. Hence, the CIMac Analytical Columns can be effectively used for the in-process and final control of various samples from different purification process steps.
CIMac PrimaS® plays a key role within BIA’s family of high-performance chromatography products for analysis and purification of mRNA. Its positive charge confers it some anion exchange behavior, but hydrogen bonding makes its selectivity entirely distinct from traditional anion exchangers.
PrimaS® features:
Multimodal chromatography ligand that combines elements of hydrogen bonding with anion exchange chromatography
Unique selectivities in many important product areas
Supports purification of single-stranded RNA at ambient temperature

Specifications
Applications:
Application: Analytical Columns

Connections (Physical):
Connector(s): 10-32 UNF coned port, 0.0625" OD tubing connection

Dimensions:
Channel Size: 2 µm
Diameter: 5.2 mm
Length: 4.95 mm

Features:
Reusable: Yes

General Specifications:
Flow Rate: 0.2 – 3 mL/min | 1 – 15 cm/min | 2 – 30 CV/min

Materials of Construction:
Materials of Construction: Poly(glycidyl methacrylate -co- ethylene dimethacrylate)

Operating Conditions:
Maximum Operating Pressure: 15 MPa | 150 bar | 2175 psi
Recommended Operating Temperature: 2 °C (36 °F) to 25 °C (77 °F)
pH Stability: Working range 2–11, cleaning in place 1–13

Physicochemical Information:
Bed Volume: 0,1 mL
Ligand: PrimaS (multimodal - anion exchange-hydrogen bonding)

Product Information:
Brand: CIMac™

Storage Conditions:
Storage Conditions: 20% EtOH