BRAND / VENDOR: Thermo Fisher
Thermo Fisher, 27-1020-02, TheraPure™ 2'-MOE-5mC Phosphoramidite, serum vial bottle
CATALOG NUMBER: 27-1020-02
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CATALOG NUMBER: 27-1020-02
1 g 2'-MOE-5mC CEP is a phosphoramidite containing 5' DMT and the nucleoside 5-methyl-cytidine (5mC) with 2'-O-methoxy-ethyl (MOE) protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methoxy-ethyl (MOE) modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 20-mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.
Features:Full chemical name– 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-N4-benzoyl-cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramiditeMolecular formula– C50H60N5O10PBase—5mCBase Protection– BzMolecular weight– 922.
0 g/molCAS number– 163759-94-2HPLC purity– ≥99%; M-11 Impurity ≤0.
01%31P NMR purity– ≥99%For Use With (Equipment): AKTA Synthesizers, Applied Biosystems Synthesizers
Form: Powder
Grade: TheraPure™
Nucleic Acid Type: RNA
Nucleoside Type: Cytidine (C)
Product Type: 2in-MOE-5mC CEP
Purity: 99%
Quantity: 1 g
Reagent Features: 2in-MOE modified
Reagent Type: Phosphoramidite
Shipping Condition: Room Temperature
Product Line: TheraPure™
Unit Size: Each
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