Thermo Fisher, 27-1604-09, TheraPure™ 2'-Fluoro-Ac-C Phosphoramidite, 20-400 finish bottle

Thermo Fisher, 27-1604-09, TheraPure™ 2'-Fluoro-Ac-C Phosphoramidite, 20-400 finish bottle 2'-Fluoro-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.
31P NMR Purity: ≥98%
CAS: 159414-99-0
Chemical Name or Material: 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-fluorocytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Description: Base: CBase Protection: Ac
For Use With (Application): Oligonucleotide synthesis
For Use With (Equipment): Expedite Synthesizers
Form: Powder
Format: Amber bottle (20-400 finish neck style)
Grade: TheraPure™
Molecular Formula: C41H49N5FO8P
Molecular Weight (g/mol): 789.
8 g/mol
Nucleic Acid Type: RNA
Nucleoside Type: Cytidine (C)
Product Type: 2in-Fluoro-Ac-C CEP
Purity: >98% (HPLC)
Quantity: 0.
25 g
Reagent Features: 2in-Fluoro modified, Fast deprotection
Reagent Type: Phosphoramidite
Shipping Condition: Room Temperature
Product Line: TheraPure™
Unit Size: Each