Thermo Fisher, 27-1607-12, 2'-Fluoro-iBu-G Phosphoramidite, standard grade, 28-400 finish bottle

Thermo Fisher, 27-1607-12, 2'-Fluoro-iBu-G Phosphoramidite, standard grade, 28-400 finish bottle 2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.
Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoroguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C44H53FN7O8P
• Base—G
• Base Protection—iBu
• Formula weight—857.
4 g/mol
• CAS number—144089-97-4
• HPLC purity—>98%
•31P NMR purity—≥98%For Use With (Equipment): MerMade Synthesizers
Form: Powder
Grade: Standard
Nucleic Acid Type: RNA
Nucleoside Type: Guanosine (G)
Product Type: 2in-Fluoro-iBu-G CEP
Purity: 98%
Quantity: 0.
5 g
Reagent Features: 2in-Fluoro modified
Reagent Type: Phosphoramidite
Shipping Condition: Room Temperature
Unit Size: Each