Product Description
Thermo Fisher, 27-1804-10, TheraPure™ rU Phosphoramidite, 20-400 finish bottle rU CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) for use in oligonucleotide synthesis. RNA phosphoramidites contain a 2'-OH protecting group, tBDMS (tert-butyl dimethylsilyl). Each base has unique protecting groups (except T and U) designed specifically to protect the RNA during the chemical synthesis process, and produce the highest amount of full length product. Alternate base protection options are also available to allow for faster deprotection and longer oligonucleotide synthesis. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30 mL Amber bottle with a 20-400 Finish neck style, which is compatible with most Expedite Systems of oligonucleotide synthesizers.
Features:
• HPLC Purity—≥99%; M-11 Impurity: ≤0.
01%
• 31P NMR Purity—≥99%; Sum of non-primary peaks in 140-152 ppm range: ≤0.
5%; No single PIII impurity >0.
3%31P NMR Purity: ≥99%
CAS: 118362-03-1
Chemical Name or Material: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-uridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Description: Base: rU
For Use With (Application): Oligonucleotide synthesis
For Use With (Equipment): Expedite Synthesizers
Form: Powder
Format: Amber bottle (20-400 finish neck style)
Grade: TheraPure™
Molecular Formula: C45H61N4O9Psi
Molecular Weight (g/mol): 861.
1 g/mol
Nucleic Acid Type: RNA
Nucleoside Type: Uridine (U)
Product Type: rU CEP
Purity: ≥99% (HPLC)
Quantity: 1 g
Reagent Type: Phosphoramidite
Shipping Condition: Room Temperature
Product Line: TheraPure™
Unit Size: Each
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