Thermo Fisher, A1122204, CD OptiCHO™ AGT™ Medium

1 L CD OptiCHO™ medium is specifically designed to offer high performance and yield with recombinant CHO cells in a chemically defined fed-batch environment. The protein-free, animal origin free formulation is designed to provide consistency and reduces the need to screen for adventitious agents. CD OptiCHO™ medium builds on Gibco™ CD CHO’s legacy of consistent cell growth and titers, while offering up to 40% better titer and cell growth over select competitors. Thanks to its low osmolality and advancedCHO CD EfficientFeed™ Liquid Nutrient Supplement Kitfeeding options, CD OptiCHO™ medium is capable of gaining 2-5 fold increases in fed-batch productivity over batch culture.
When to Use CD OptiCHO™ Medium
• You are using a transfected CHO cell line other than CHO K1, GS CHO or CHO-S™ cell lines
• Optimization of feeding strategies will be part of your base medium selection testing in an effort to maximize productivity
• Your CHO cell line is “finicky,” i.
e. hard to grow or adaptWhen to Consider Another Gibco™ MediumConsiderCD FortiCHO™ mediumwhen:
• The cell line you are using is a transfected CHO K1, GS CHO or CHO-S™ cell line
• Maximum batch culture cell densities and protein titers are needed
• You have time to adapt cells into a new medium in an effort to maximize titers
• Cell health at harvest is a priority for downstream processingConsiderCD CHO mediumwhen:
• Your GS CHO cells are recommended to be grown in CD CHO medium
• Your cells have been successfully cultured in CD CHO medium in the past and your process is nearing a regulatory filing (DMF available)ConsiderCD DG44 mediumwhen:
• You use parental DG44 or DXB11 CHO cells (dhfr-)Liquid Media FormulationsGibco™ AGT™ media are also available in aliquid formatthat offers the same performance and formulation as the AGT™ media format. Gibco™ liquid media are manufactured animal origin-free with the same complete, serum-free, protein-free, chemically-defined formulation and performance as their AGT™ media counterparts.
Design Your Own Media Specific to Your NeedsWhether it’s a bench-level experiment or large scale biomanufacturing process, we offer specialized formats, packaging, and quality levels specific to your needs. WithGibco™ cGMP Media Custom Servicesyou can put the manufacturing power and years of technical experience of our R&D and Bioproduction Application Specialists to work for you.
Cell Line: CHO
Culture Environment: CO2
Endotoxin Level: Low
Format: Securitainer Capped Vial
Included Antibiotics: No antibiotics
Inorganic Salts: Magnesium, Sodium Phosphate
Product Line: AGT™, Gibco™
Product Type: CD OptiCHO AGT Medium
Purity or Quality Grade: Certified
Quantity: 1 L
Reconstituted Volume: 1 L
Remarks: Medium does not support wild type DG44 cells
Shipping Condition: Wet Ice
Classification: Animal Origin-free, Chemically-defined, Protein-free, Serum-free
Culture Type: Suspension Cell Culture
Form: Powder (AGT)
Serum Level: Serum-free
Sterility: Non-sterile
With Additives: High Glucose, Sodium Pyruvate, Sodium Bicarbonate
Without Additives: No Glutamine, No Phenol Red
Unit Size: Each