Product Description
Thermo Fisher, PV3508, Fluorescein-CREBtide Substrate A fluorescein-labeled peptide substrate that is based upon the CREB ( cAMP responsive element binding) protein. The peptide substrate is phosphorylated by a wide range of Ser/Thr kinases.
For use in combination with the LanthaScreen™ Tb-CREB [pSer133] antibody (PV3542) to evaluate inhibitors in medium to high throughput screening applications.
Amino Acid Sequence: Fluorescein- KRREILSRRPSYR
Assay Entry: Biochemical terbium phospho-specific activity
Label or Dye: FITC (Fluorescein)
Molecular Weight (g/mol): 2076 Da
Quantity: 1 mg
Shipping Condition: Dry Ice
Substrate: Fluorescein-CREBtide
Target Entry: AMPK (A2/B1/G1), STK22D, CAMK2B, CHEK1, MAPKAPK2, PASK, PIM2, PRKCN, PRKD2, PRKG2, RPS6KA5, AMPK (A1/B1/G1), AURKA, CAMK1D, CAMK4, CHEK2, MAPKAPK3, PIM1, PKN1, PRKD1, PRKG1, RPS6KA4, CAMK1
Validated Kinases: AMPK, AURKA, CAMK1, CAMKID, CAMK2A, CAMK2B, CAMK4, CHEK1, CHEK2, MAPKAPK2, MAPKAPK3, PASK, PIM1, PIM2, PKN1, PRKACA, PRKD1, PRKD2, PRKG1, PRKG2, RPS6KA4, RPS6KA5, STK22D
Detection Method: Fluorescence
Substrate Properties: Peptide-Based Substrate
Substrate Type: Kinase Substrate
Target Enzyme: Serine/Threonine Kinases
Unit Size: Each
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