Thermo Fisher, PV4812, Fluorescein-MAP2K1

Thermo Fisher, PV4812, Fluorescein-MAP2K1 Inactive MAP2K1 (MEK1) has been labeled with fluorescein, and is a substrate for MAPK family members.
For use in combination with the LanthaSreen™ Tb-MAP2K1 [pSer217/221] Antibody (PV4813) to evaluate inhibitors in medium to high throughput screening applications.
Assay Entry: Biochemical terbium phospho-specific activity
Gene ID (Entrez): 10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Label or Dye: FITC (Fluorescein)
Molecular Weight (g/mol): 50000 Da
Quantity: 20 nmol
Shipping Condition: Dry Ice
Substrate: MAP2K1
Target Entry: MAP3K2, RAF1 (cRAF) Y340D Y341D, MAP3K10, MAP3K9, MAP3K7/MAP3K7IP1, MAP3K5, MAP3K11, BRAF V599E, BRAF, MAP3K8, MAP3K3
Validated Kinases: BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
Detection Method: Fluorescence
Substrate Properties: Protein-Based Substrate
Substrate Type: Kinase Substrate
Target Enzyme: Serine/Threonine Kinases
Unit Size: Each