Product Description
Thermo Fisher, PV4901, Fluorescein-ERM (LRRKtide) A fluorescein-labeled peptide substrate based upon ezrin/radixin/moesin (ERM) that is phosphorylated by LRRK2 and LRRK2 mutants.
For use in combination with the LanthaScreen™ Tb-anti-ERM (pLRRKtide) Antibody (PV4899) to evalute inhibitors in medium to high throughput screening applications.
Amino Acid Sequence: Fluorescein-GAGRLGRDKYKTLRQIRQ
Assay Entry: Biochemical terbium phospho-specific activity
Gene ID (Entrez): 120892
Label or Dye: FITC (Fluorescein)
Molecular Weight (g/mol): 2475.
8 Da
Quantity: 1 mg
Shipping Condition: Dry Ice
Substrate: ERM (LRRKtide)
Target Entry: LRRK2 D1994A, LRRK2 R1441C, LRRK2 I2020T, LRRK2 G2019S, LRRK2
Validated Kinases: LRRK2
Detection Method: Fluorescence
Substrate Properties: Peptide-Based Substrate
Substrate Type: Kinase Substrate
Target Enzyme: Serine/Threonine Kinases
Unit Size: Each
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