Thermo Fisher, PV5693, Alexa Fluor™ 647-Poly-GT Peptide Substrate

1 nmol A general AlexaFluor647-labeled peptide substrate consisting of a polymer of glutamate, and tyrosine that is used to monitor tyrosine kinase acitivty.
For use in combination with the LanthaScreen™ Eu-PY20 Antibody (Cat. No. PV5696) to evaluate inhibitors in medium to high throughput screening applications.
Assay Entry: Biochemical europium phospho-specific activity
Color: Far-Red
Excitation/Emission: 340/665 nm
Label or Dye: Alexa Fluor™ 647
Product Line: LanthaScreen™
Quantity: 1 nmol
Shipping Condition: Dry Ice
Substrate: Random (Glu:Tyr) polymer in a ratio of 4:1
Target Entry: ABL1 G250E, CSF1R, CSK, EPHA5, KIT, PDGFRA V561D, SYK, TYRO3, ZAP70, FGFR1, FGFR2, EGFR, EPHB2, FGFR4, IGF1R, LYNA, MATK, MERTK, NTRK3, RET V804L, TEK, FLT1, MUSK, SRCN1, ABL1 E255K, EPHA4, FYN, PTK2, PTK2B, RET, ABL1 T315I, EPHA3, EPHB4, FLT3, FLT4, INSR, LCK, YES1, EGFR L858R, ERBB4, KDR, MET, TNK2, ABL1, ABL2, AXL, FGFR3, FGR, HCK, KIT V654A, EPHA1, EPHA8, EPHB3, INSRR, LYNB, NTRK1, PDGFRA D842V, SRMS, EGFR L861Q, EPHA2, FER, LTK, PDGFRA, EPHA7, EPHB1, FRK, ITK, FLT3 D835Y, SRC, BTK, FES, ERBB2, NTRK2
Technique: TR-FRET
Validated Kinases: EGFR
Detection Method: Fluorescence
Form: Liquid
Substrate Properties: Peptide-Based Substrate
Substrate Type: Kinase Substrate
Target Enzyme: Tyrosine Kinases
Unit Size: Each