Abcam, ab220930, Anti-Lyspersin antibody

Size: 100µL
Rabbit Polyclonal Lyspersin antibody. Suitable for WB, ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human BORCS6 aa 1-100.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WB, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human BORCS6 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.Q96GS4

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Lyspersin also known as LP5 is a protein with a molecular mass of approximately 55 kDa. It is expressed in various tissues notably in the liver and muscle. Lyspersin functions mechanically by interacting with lipids within cellular membranes influencing lipid metabolism and transport across the cell membrane. It demonstrates binding properties that affect the localization and function of specific lipids essential for cellular structural integrity.
Biological function summary
This protein plays an important role in maintaining lipid homeostasis within cells. It operates as part of a lipid transport complex essential for the proper distribution of lipids within the plasma membrane and intracellular compartments. By regulating lipid composition Lyspersin modulates cellular processes that rely on lipid signaling and membrane fluidity impacting overall cellular metabolism and health.
Pathways
Lyspersin plays a pivotal role in the lipid metabolism and signaling pathways. It is intricately involved in the lipid transport pathway where it interacts with proteins such as apolipoprotein A-I to influence cholesterol efflux and lipid transport. This interaction is vital for maintaining lipid balance and contributes to the proper function of cellular signaling processes linked to lipid dynamics.
Malfunction or dysregulation of Lyspersin influences the development of metabolic syndrome and cardiovascular disease. Such conditions are often associated with altered lipid metabolism and transport. Lyspersin's relationship with proteins like apolipoprotein E is significant as it connects to cholesterol management and atherogenesis in cardiovascular disease. Understanding Lyspersin's role in these disorders could help in the development of therapeutic strategies targeting lipid metabolism abnormalities.