Product Description
Please contact our sales representative for bulk pricing quotations. Mouse IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) due to its ability to inhibit cytokine production by TH1 clones. IL-10 is expressed in activated CD8 + and CD4 + T cells, activated monocytes, mast cells, and Ly-1 B cells. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The functions of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed-type hypersensitivity response, and stimulation of the TH2 cell response, which results in elevated antibody production. ELISA Development Systems Engineered for Sensitive, Precise and Reliable Serum and Plasma Cytokine Quantitation. BioLegend's ELISA Max™ Sets provide all the time-savings, convenience and performance of a high-end, commercial ELISA kit for a fraction of the price! BioLegend's ELISA Max™ Sets, in two appealing formats, address the need for sensitivity, accuracy, dependability, and versatility of an ELISA development system, while providing maximum cost effectiveness, value, and ease of use. Both the ELISA Max™ Set Standard and ELISA Max™ Set Deluxe are specifically engineered for accurate recovery and measurement of analytes in complex fluids, such as serum and plasma (as well as activated cell cultures) without any interference by confounding serum factors, such as heterophilic antibody or rheumatoid factor.
20plates
Verified Reactivity: Mouse
Application: ELISA
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Product Citations: Asai A, et al. 2012. Immunobiology. 217:711. PubMed Yang JM, et al. 2022. Sci Adv. 8:eabo0183. PubMed Lundahl MLE, et al. 2022. Elife. 11:. PubMed Hasnat MA, et al. 2022. Immunol Cell Biol. 100:605. PubMed Rengachar P, et al. 2022. Biomolecules. 12: . PubMed Rengachar P, et al. 2023. Front Endocrinol (Lausanne). 13:1053879. PubMed Yan K, et al. 2022. Phytother Res. 36:2161. PubMed Santos I, et al. 2020. Proc Natl Acad Sci U S A. 117:12281. PubMed Espinosa-Cueto P, et al. 2017. PLoS One.. 10.1371/journal.pone.0182126. PubMed Wang Y, et al. 2021. Andrologia. 53:e14239. PubMed Yu Y, et al. 2022. iScience. 25:105004. PubMed Singh I, et al. 2018. Immunobiology. 223:549. PubMed Gomes MT, et al. 2022. J Biol Chem. 298:102034. PubMed Th?nert R, et al. 2017. Nat Commun. 8:14268. PubMed Lin YZ, et al. 2022. Comput Struct Biotechnol J. 20:241. PubMed Lajqi T, et al. 2022. Biomedicines. 10:. PubMed Croasdell A, et al. 2016. J Immunol. 196: 2742 - 2752. PubMed Hsieh PS, et al. 2021. Exp Ther Med. 188:21. PubMed Colaço HG, et al. 2021. Immunity. 54:53:00. PubMed Stravinskas Durigon T, et al. 2018. J Innate Immun. 10:279. PubMed Iizasa E, et al. 2021. Nat Commun. 12:2299. PubMed Sousa AH, et al. 2021. Can J Physiol Pharmacol. 99:1324. PubMed Singh N, et al. 2016. J Immunol. 196: 1108 - 1122. PubMed Kumar RK, et al. 2021. Vascul Pharmacol. 138:106838. PubMed Egli N, et al. 2015. PLoS One. 10: 0142741. PubMed Lajqi T, et al. 2021. Int J Mol Sci. 22:. PubMed Fenoy I, et al. 2015. Exp Parasitol. 154: 47-50. PubMed Andrade-Sousa A, et al. 2016. PLoS One. 11: 0163420. PubMed Hu Y, et al. 2017. Biochim Biophys Acta. 10.1016/j.bbadis.2017.06.001. PubMed Fenoy IM, et al. 2015. Immunobiology. 22: 641-648. PubMed Jones C, et al. 2014. PLoS One. 9:90855. PubMed Murayama M, et al. 2015. Nat Commun. 6: 8483. PubMed Zhang Z, et al. 2020. Front Immunol. 11:583276. PubMed Guo Z, et al. 2022. Neurobiol Pain. 12:100096. PubMed
Standard Range: 31.3-2,000 pg/mL
Cell Sources: Activated CD8+ T cells, Th0, Th2 subset of CD4+ T cells, Ly-1+ B cells, monocytes, macrophages, keratinocytes
Cell Type: Tregs
Biology Area: Immunology
Molecular Family: Cytokines/Chemokines
Gene ID: 16153
UniProt: View information about IL-10 on UniProt.org
Regulatory Status: RUO
Other Names: IL-10 ELISA Kit
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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