Product Description
Size: 20ul / 150ul
The CD68 (66231-2-Ig) by Proteintech is a Monoclonal antibody targeting CD68 in IHC, IF-P, ELISA applications with reactivity to human samples
66231-2-Ig targets CD68 in IHC, IF-P, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive IHC detected in: human tonsillitis tissue, human appendicitis tissue, human colon cancer tissue, human liver cancer tissue, human lung cancer tissue, human urothelial carcinoma tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Positive IF-P detected in: human tonsillitis tissue
Recommended dilution
Immunohistochemistry (IHC): IHC : 1:1000-1:6000
Immunofluorescence (IF)-P: IF-P : 1:3000-1:12000
Background Information
CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.
Specification
Tested Reactivity: human
Cited Reactivity: human, pig
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Ag22815 Product name: Recombinant human CD68 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 29-319 aa of BC015557 Sequence: SATLLPSFTVTPTVTESTGTTSHRTTKSHKTTTHRTTTTGTTSHGPTTATHNPTTTSHGNVTVHPTSNSTATSQGPSTATHSPATTSHGNATVHPTSNSTATSPGFTSSAHPEPPPPSPSPSPTSKETIGDYTWTNGSQPCVHLQAQIQIRVMYTTQGGGEAWGISVLNPNKTKVQGSCEGAHPHLLLSFPYGHLSFGFMQDLQQKVVYLSYMAVEYNVSFPHAAQWTFSAQNASLRDLQAPLGQSFSCSNSSIILSPAVHLDLLSLRLQAAQLPHTGVFGQSFSCPSDRS Predict reactive species
Full Name: CD68 molecule
Calculated Molecular Weight: 37 kDa
GenBank Accession Number: BC015557
Gene Symbol: CD68
Gene ID (NCBI): 968
RRID: AB_2881622
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein G purification
UNIPROT ID: P34810
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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