Proteintech, 98078-1-RR, Anti-Human CTLA-4/CD152 Rabbit Recombinant Antibody

Size: 100ug The CTLA-4/CD152 (98078-1-RR) by Proteintech is a Recombinant antibody targeting CTLA-4/CD152 in IHC, FC applications with reactivity to human samples 98078-1-RR targets CTLA-4/CD152 in IHC, FC applications and shows reactivity with human samples. Tested Applications Positive IHC detected in: human tonsillitis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Positive FC detected in: PHA treated human PBMCs Recommended dilution Immunohistochemistry (IHC): IHC : 1:500-1:2000 Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information CTLA-4, also known as CD152, belonging to the immunoglobulin superfamily, is primarily found on activated T cells and regulatory T cells (Tregs). CTLA-4 is closely related to the T-cell costimulatory CD28, and both molecules bind to B7-1 and B7-2 on antigen-presenting cells. CTLA-4 acts as a negative regulatory molecule of T-cell responses. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg0972 Product name: Recombinant Human CTLA4 protein (His Tag) Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 36-161 aa of BC070162 Sequence: KAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSD Predict reactive species Full Name: cytotoxic T-lymphocyte-associated protein 4 Calculated Molecular Weight: 223 aa, 25 kDa GenBank Accession Number: BC070162 Gene Symbol: CTLA4 Gene ID (NCBI): 1493 RRID: AB_3672225 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P16410 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.