Product Description
Size: 100ug
The CCL20/MIP-3 alpha (98500-1-RR) by Proteintech is a Recombinant antibody targeting CCL20/MIP-3 alpha in FC (Intra) applications with reactivity to rat samples
98500-1-RR targets CCL20/MIP-3 alpha in FC (Intra) applications and shows reactivity with rat samples.
Tested Applications
Positive FC (Intra) detected in: Transfected HEK-293T cells
Recommended dilution
Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension
Background Information
CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.
Specification
Tested Reactivity: rat
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Eg3237 Product name: Recombinant Rat CCL20/MIP-3 alpha protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 27-96 aa of NM_019233.1 Sequence: SNFDCCLTYTKNVYHHARNFVGFTTQMADEACDINAIIFHLKSKRSVCADPKQIWVKRILHLLSLRTKKM Predict reactive species
Full Name: chemokine (C-C motif) ligand 20
Calculated Molecular Weight: 11 kDa
GenBank Accession Number: NM_019233.1
Gene Symbol: Ccl20
Gene ID (NCBI): 29538
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: P97884
Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.
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Collaboration
Tony Tang
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