Abcam, ab120371, NS309, K+ channel activator

Size: 10mg / 50mg
MW 231.03 Da, Purity >98%. Potent activator of human Ca2+ -activated K+ channels of SK and IK types, selective over BK type channels (EC50 = 10 nM for increasing hIK current). At least 1000 times more potent than 1-EBIO (ab120258). Can be used in conjunction with CyPPA (ab120829) to distinguish SK1 and SK3 subtypes.
Key facts
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:231.03 Da,
Molecular formula:C8H4Cl2N2O2,
PubChem:11637204,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:CID 11637204,
Biological description:Potent activator of human Ca2+ -activated K+ channels of SK and IK types, selective over BK type channels (EC50 = 10 nM for increasing hIK current). At least 1000 times more potent than 1-EBIO (ab120258). Can be used in conjunction with CyPPA (ab120829) to distinguish SK1 and SK3 subtypes.,
Canonical smiles:C1=CC(=C(C2=NC(=O)C(=C21)NO)Cl)Cl,
Isomeric smiles:C1=CC(=C(C2=NC(=O)C(=C21)NO)Cl)Cl,
InChi:InChI=1S/C8H4Cl2N2O2/c9-4-2-1-3-6(5(4)10)11-8(13)7(3)12-14/h1-2,14H,(H,11,12,13),
InChiKey:CVOUSAVHMDXCKG-UHFFFAOYSA-N,
IUPAC Name:6,7-dichloro-3-(hydroxyamino)indol-2-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months