Abcam, ab120592, LY 344864 hydrochloride, 5-HT1F agonist

Size: 10mg / 50mg
MW 387.88 g/mol, Purity >98%. Selective, potent, full 5-HT 1F agonist (EC 50 = 3 nM). Selectivity is 80-fold greater than for other 5-HT receptor subtypes, K i values are 0.53 (5-HT 1A ), 0.549 (5-HT 1B ), 0.575 (5-HT 1D ), 1.415 (5-HT 1E ), 3.935 (5-HT 2A ), 1.695 (5-HT 2B ), 3.499 (5-HT 2C ) and 4.851 (5-HT 7 ). Able to reduce central sensitization and dural inflammation in vivo .
Key facts
CAS number:186544-26-3,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:387.88 g/mol,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mMSoluble in water to 5 mM,
Biological description:Selective, potent, full 5-HT1F agonist (EC50 = 3 nM). Selectivity is 80-fold greater than for other 5-HT receptor subtypes, Ki values are 0.53 (5-HT1A), 0.549 (5-HT1B), 0.575 (5-HT1D), 1.415 (5-HT1E), 3.935 (5-HT2A), 1.695 (5-HT2B), 3.499 (5-HT2C) and 4.851 (5-HT7). Able to reduce central sensitization and dural inflammation in vivo.,
IUPAC Name:N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months