Abcam, ab120713, Loperamide hydrochloride, mu opioid receptor agonist

Size: 1g
MW 513.5 Da, Purity >99%. Peripheral selective μ opioid receptor agonist. Ki values are 3, 48 and 1156 nM for opioid receptor subtypes μ, δ and κ, respectively. High doses allow central μ receptor activation. Antidiarrheal, antipruritic and antihyperalgesic agent.
Key facts
CAS number:34552-83-5,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:513.5 Da,
Molecular formula:C29H34Cl2N2O2,
PubChem:71420,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM and in ethanol to 50 mM (with warming),
Biochemical name:Loperamide hydrochloride,
Biological description:Peripheral selective μ opioid receptor agonist. Ki values are 3, 48 and 1156 nM for opioid receptor subtypes μ, δ and κ, respectively. High doses allow central μ receptor activation. Antidiarrheal, antipruritic and antihyperalgesic agent.,
Canonical smiles:CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl,
InChi:InChI=1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H,
InChiKey:PGYPOBZJRVSMDS-UHFFFAOYSA-N,
IUPAC Name:4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months