Abcam, ab120795, Rhodadyn™ C10, cell-permeable dynamin I inhibitor

Size: 5mg
MW 350.49 g/mol, Purity >98%. Highly potent cell-permeable dynamin I GTPase activity inhibitor (IC 50 values are 7.1 and 30.3 μM at dynamin I and dynamin II, respectively). Blocks clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture (IC 50 = 7.0 μM). Rhodadyn™ B10 negative control also available (ab120796). Robertson J et al . The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012).
Key facts
CAS number:1367579-04-1,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:350.49 g/mol,
Molecular formula:C17H22N2O2S2,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biological description:Highly potent cell-permeable dynamin I GTPase activity inhibitor (IC50 values are 7.1 and 30.3 μM at dynamin I and dynamin II, respectively). Blocks clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture (IC50 = 7.0 μM).Rhodadyn™ B10 negative control also available (ab120796).Robertson J et al. The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012).,
IUPAC Name:(5Z)-5-[4-[3-(Dimethylamino)propoxy]benzylidene]-3-ethyl-2-thioxo-1,3-thiazolidin-4-one

Product details:
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovations Ltd. Rhodadyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months