Abcam, ab120848, ML7, myosin light chain kinase inhibitor

Size: 10mg / 50mg
MW 452.7 Da, Purity >99%. Potent and selective myosin light chain kinase inhibitor (MLCK) (K i = 300 nM). Also inhibits PKA and PKC (K i values are 21 and 42 μM, respectively). Cell-permeable. Inhibits tumor cell growth.
Key facts
CAS number:109376-83-2,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:452.7 Da,
Molecular formula:C15H18ClIN2O2S,
PubChem:9803932,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:1-((5-Iodonaphthalen-1-yl)sulfonyl)-1,4-diazepane hydrochloride,
Biological description:Potent and selective myosin light chain kinase inhibitor (MLCK) (Ki = 300 nM). Also inhibits PKA and PKC (Ki values are 21 and 42 μM, respectively). Cell-permeable. Inhibits tumor cell growth.,
Canonical smiles:C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3I.Cl,
InChi:InChI=1S/C15H17IN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H,
InChiKey:KDDALCDYHZIZMH-UHFFFAOYSA-N,
IUPAC Name:1-(5-iodonaphthalen-1-yl)sulfonyl-1,4-diazepane;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months