Abcam, ab120891, BIO, GSK3 inhibitor; cell-permeable

Size: 10mg / 25mg
MW 356.18 g/mol, Purity >98%. Highly potent, selective, reversible and ATP-competitive inhibitor of GSK3α/β (IC 50 values are 5 (GSK3α/β), 83 (CDK5/p25), 300 (CDK2/cyclin A) and 320 nM (CDK1/cyclin B)). Activates the Wnt signaling pathway in vitro maintaining self-renewal and pluripotency in ESC. Cell-permeable.
Key facts
CAS number:667463-62-9,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:356.18 g/mol,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM,
Biological description:Highly potent, selective, reversible and ATP-competitive inhibitor of GSK3α/β (IC50 values are 5 (GSK3α/β), 83 (CDK5/p25), 300 (CDK2/cyclin A) and 320 nM (CDK1/cyclin B)). Activates the Wnt signaling pathway in vitro maintaining self-renewal and pluripotency in ESC. Cell-permeable.,
Isomeric smiles:O/N=C1/C(=C2C(=O)NC3CC(BR)CCC/23)NC2CCCCC12,
IUPAC Name:(2'Z,3'E)-6-Bromoindirubin-3'-oxime

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions