Abcam, ab120914, Xestospongin C, IP3 receptor antagonist

Size: 10µg / 50µg / 100µg
MW 446.72 g/mol, Purity >90%. Potent, selective, reversible IP 3 receptor antagonist (IC 50 = 350 nM). Inhibits IP 3 -mediated Ca 2+ release from ER and SR. 30-Fold selectivity over ryanodine receptor. Inhibits voltage-dependent Ca 2+ and K + channels at higher concentrations. Cell-permeable.
Key facts
CAS number:88903-69-9,
Purity:>90%,
Form:SolidSee storage information,
Molecular weight:446.72 g/mol,
Nature:Synthetic,
Solubility:Soluble in DMSO to 2 mMSoluble in ethanol to 2 mM,
Biological description:Potent, selective, reversible IP3 receptor antagonist (IC50 = 350 nM). Inhibits IP3-mediated Ca2+ release from ER and SR. 30-Fold selectivity over ryanodine receptor. Inhibits voltage-dependent Ca2+ and K+ channels at higher concentrations. Cell-permeable.,
Isomeric smiles:C1CCC[C@H]2CCCN3CCC(CCCCCCC4CCCN5CCC(CC1)O[C@H]45)O[C@H]23,
IUPAC Name:(1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions