Abcam, ab120931, PIK 75 hydrochloride, p110alpha PI3K inhibitor

Size: 5mg / 25mg
MW 488.74 g/mol, Purity >98%. Selective inhibitor of p110α (IC 50 values are 5.8, 76 nM and 1.3 μM at p110α, p110γ and p110β, respectively). Inhibits production of PIP 2 and PIP 3 in adipocytes, phosphorylation of Akt and activation of mTORC1. Cell-permeable.
Key facts
CAS number:372196-77-5,
Purity:>98%,
Molecular weight:488.74 g/mol,
Molecular formula:C16H14BrN5O4S.HCl,
Nature:Synthetic,
Solubility:Soluble in DMSO to 5 mM,
Biological description:Selective inhibitor of p110α (IC50 values are 5.8, 76 nM and 1.3 μM at p110α, p110γ and p110β, respectively). Inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of Akt and activation of mTORC1. Cell-permeable.,
Isomeric smiles:BRC1=CN2C(C=C1)=NC(/C=N/N(S(C3=CC([N+]([O-])=O)=CC=C3C)(=O)=O)C)=C2,
IUPAC Name:2-Methyl-5-nitrobenzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months