Abcam, ab120951, Nifuroxazide, JAK/STAT signaling inhibitor

Size: 100mg
MW 275.22 g/mol, Purity >98%. JAK/STAT signaling inhibitor. Nitrofuran antibiotic. Inhibits JAK2 and Tyk2 phosphorylation and subsequent downstream STAT3 inhibition (EC 50 = 3 μM). Antidiarrheal. Shows little effect on Akt, NF-κB, JAK1, MAPK and Src signaling.
Key facts
CAS number:965-52-6,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:275.22 g/mol,
Molecular formula:C12H9N3O5,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biological description:JAK/STAT signaling inhibitor. Nitrofuran antibiotic. Inhibits JAK2 and Tyk2 phosphorylation and subsequent downstream STAT3 inhibition (EC50 = 3 μM). Antidiarrheal. Shows little effect on Akt, NF-κB, JAK1, MAPK and Src signaling.,
IUPAC Name:4-Hydroxybenzoic acid 2-[(5-nitro-2-furanyl)methylene]hydrazide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months