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BRAND / VENDOR: Abcam

Abcam, ab120980, KN-93 (water soluble), CaMK II inhibitor

CATALOG NUMBER: ab120980
السعر العادي$0.99
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Product Description

Size: 1mg
MW 599 Da, Purity >99%. Potent, specific and cell-permeable calmodulin-dependent protein kinase (CaMK) II inhibitor (IC 50 = 370 nM). Also a potent and direct extracellular open channel voltage-gated potassium channel blocker (IC 50 = 307 nM for Kv1.5); independent of CaM kinase II inhibition. Water soluble.
Key facts
CAS number:1188890-41-6,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:599 Da,
Molecular formula:C26H32ClN2O8PS,
PubChem:16760530,
Nature:Synthetic,
Solubility:Soluble in water to 100 mMSoluble in DMSO to 100 mM,
Biochemical name:KN-93 Phosphate,
Biological description:Potent, specific and cell-permeable calmodulin-dependent protein kinase (CaMK) II inhibitor (IC50 = 370 nM). Also a potent and direct extracellular open channel voltage-gated potassium channel blocker (IC50 = 307 nM for Kv1.5); independent of CaM kinase II inhibition. Water soluble.,
Canonical smiles:CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O,
Isomeric smiles:CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O,
InChi:InChI=1S/C26H29ClN2O4S.H3O4P/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25;1-5(2,3)4/h3-16,30H,17-20H2,1-2H3;(H3,1,2,3,4)/b6-5+;,
InChiKey:NNKJTPOXLIILMB-IPZCTEOASA-N,
IUPAC Name:N-[2-[[[(E)-3-(4-chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide;phosphoric acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions


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